Christos Velanis discusses the polycomb group complex, domesticated transposons and the future of scientific funding.

Christos Velanis works at the University of Edinburgh and discusses work published in PloS Genetics entitled ‘The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2)‘.

Pumi Perera is co-first author on this work from the Goodrich lab that is the follow-on to research published in PLoS Genetics in 2015 ‘Kicking against the PRCs – A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2‘. At the time GARNet talked to Justin Goodrich about this paper

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